Some of the controllers below have been designed for use with Playstation One and PS2 game consoles. With additional controller adapters, most other games machines, PCs and Macs can be made accessible. Click on the images below for more details on each controller.
Please feel free to e-mail for help on anything that is unclear.

From OneSwitch.org.uk

Suitable for left or right handed play. Compatible with many but not all Playstation 2 games with a switchable thumb-stick.

From OneSwitch.org.uk

A unique controller that can be used in three different ways: traditional, separated and one handed. Playstation One and PS2 compatible.

From OneSwitch.org.uk (UK) and Broadened Horizons (USA)

A well built controller from HORI that is best for left hand play, but can be used by right handed gamers too. Playstation one and PS2 compatible.

From OneSwitch.org.uk

Designed for use with the Playstation One console, this controller is well suited to many older games that do not require analogue control.

Some button functions can be changed, making play easier.

From OneSwitch.org.uk

Ideal for Dancing games, and also usable with most Playstation One games. LEDs illuminate when the direction buttons are pressed.

Available from eDimensional

The Ben Heckendorm designed "Access Controller". Wireless with interchangable control pods. Compatible with PS3, PS2 and PCs.

Read a review at Game Forward.

From Consoles and Gadgets - Second hand wanted by OneSwitch.

Highly suitable for left or right handed play. Compatible with Playstation 2 games. This controller also features a small RESET button.

From Amazon and eBay

Nintendo Wii with Wii-mote motion tracking one handed controller.

N.B. Robert Merritt has posted a list of games that are one-hand compatible.

From Broadened Horizons

Nintendo Wii remote controller with switch interface for the A button and B trigger and wrist straps.

Due August 2009 via Pad Fynder Interactive

PS3 and PC motion sensitive controller. The finished controller is said to feature a hand strap and 11 different control configurations. Designed for left or right handed play.

There are a number of people and organisations that may be able to build you a tailor made controller at a price.

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Related Accessible Gaming LINKS

One Hand Gaming News - Via the OneSwitch.org.uk Blog.

Controller Adapters - Enabling Playstation controllers to be used on alternative games consoles and computers.

Game-Accessibility forums - Direct link to a one-handed gamers forum.